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These changes were accompanied by marked reductions in expression of Sox9 and collagen type 10 mRNA levels (Figure 3d and 3e)

Importantly, combination of metformin and radiation significantly increased cell death, when compared to irradiated vehicle controls, highlighting the potential role for altered cell death in the metformin-mediated radiosensitisation of these cell lines

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LGGs with NF1 mutations show greater T cell infiltration, whereas mesenchymal GBMs demonstrate substantial but often ineffective T cell presence

Nutrition and cognitive impairment in the elderly